Concept: The Second Republic of Ghana (1969–1972) had a Prime Minister under a new constitution.Explanation:The Second Republic began after military rule ended in 1969.Dr K. A. Busia became Prime Minister of Ghana during this period.Dr Hilla Limann was President of the Third Republic, and Dr Kwame Nkrumah led the First Republic.Answer: B. Dr K. A. Busia.