Concept:A quadratic expression is a perfect square if it can be written as the square of a linear binomial.Explanation:Let 4x2+5kx+10=(2x+a)2.Expanding, (2x+a)2=4x2+4ax+a2.Comparing constants: a2=10, so a=10.Comparing the coefficient of x: 5k=4a=410.Therefore, k=5410.Answer:k=5410, which is option D.